Entry Detail



General Information

Database ID:BRCA43729
Cancer Type:breast cancer
Dataset:GSE86978
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:PVT1
Full Name:Pvt1 oncogene
Category:lncRNA
Synonyms:LINC00079|MIR1204HG|NCRNA00079|onco-lncRNA-100
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):127794533End Site(bp):128101253
Gene Summary:This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]
External Links:
Ensembl ID:ENSG00000249859
HGNC ID:HGNC:9709
Entrez Gene:5820



Expression Profile of PVT1 Gene

 







Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
miRNA targets:NA
Display: