ctcRbase

Entry Detail

---



General Information

Database ID: BRCA44066 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: L3MBTL3 Full Name: L3MBTL3, histone methyl-lysine binding protein Category: mRNA Synonyms: MBT-1|MBT1 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 130013699 End Site(bp): 130141451 Gene Summary: This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016] External Links: Ensembl ID: ENSG00000198945 HGNC ID: HGNC:23035 Entrez Gene: 84456

Expression Profile of L3MBTL3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-93-5p YES YES YES Display: