ctcRbase

Entry Detail

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General Information

Database ID: BRCA44197 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: CBFA2T3 Full Name: CBFA2/RUNX1 translocation partner 3 Category: mRNA Synonyms: ETO2|MTG16|MTGR2|RUNX1T3|ZMYND4 Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 88874858 End Site(bp): 88977204 Gene Summary: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] External Links: Ensembl ID: ENSG00000129993 HGNC ID: HGNC:1537 Entrez Gene: 863

Expression Profile of CBFA2T3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-128-3p YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-185-5p YES NO NO hsa-miR-191-5p YES YES NO hsa-miR-195-5p YES NO YES hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-219a-5p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES NO YES hsa-miR-599 YES YES NO hsa-miR-876-5p YES YES YES hsa-miR-877-5p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-96-5p YES NO YES hsa-miR-98-5p YES NO YES Display: