ctcRbase

Entry Detail

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General Information

Database ID: BRCA45079 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: HMGCS2 Full Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2 Category: mRNA Synonyms: - Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 119747996 End Site(bp): 119768905 Gene Summary: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000134240 HGNC ID: HGNC:5008 Entrez Gene: 3158

Expression Profile of HMGCS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-873-5p YES YES NO Display: