| ncRNA Symbol: | PARD6A |
| Full Name: | par-6 family cell polarity regulator alpha |
| Category: | mRNA |
| Synonyms: | PAR-6A|PAR6|PAR6C|PAR6alpha|TAX40|TIP-40 |
| Chromosome: | chr16 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 67660946 | End Site(bp): | 67662778 |
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| Gene Summary: | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
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