ctcRbase

Entry Detail

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General Information

Database ID: BRCA45392 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CGNL1 Full Name: cingulin like 1 Category: mRNA Synonyms: JACOP|PCING Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 57375967 End Site(bp): 57550727 Gene Summary: This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000128849 HGNC ID: HGNC:25931 Entrez Gene: 84952

Expression Profile of CGNL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-186-5p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-214-3p YES NO NO hsa-miR-219a-5p YES YES YES hsa-miR-424-5p YES NO YES hsa-miR-497-5p YES NO YES Display: