ctcRbase

Entry Detail

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General Information

Database ID: BRCA45849 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: BCKDHB Full Name: branched chain keto acid dehydrogenase E1 subunit beta Category: mRNA Synonyms: BCKDE1B|BCKDH E1-beta|E1B Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 80106647 End Site(bp): 80346270 Gene Summary: This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000083123 HGNC ID: HGNC:987 Entrez Gene: 594

Expression Profile of BCKDHB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-miR-101-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-494-3p YES YES NO Display: