ctcRbase

Entry Detail

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General Information

Database ID: BRCA46048 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TAF5 Full Name: TATA-box binding protein associated factor 5 Category: mRNA Synonyms: TAF(II)100|TAF2D|TAFII-100|TAFII100 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 103367967 End Site(bp): 103389065 Gene Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000148835 HGNC ID: HGNC:11539 Entrez Gene: 6877

Expression Profile of TAF5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-101-3p YES YES NO hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-191-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-98-5p YES YES NO Display: