| ncRNA Symbol: | AKR1C2 |
| Full Name: | aldo-keto reductase family 1 member C2 |
| Category: | mRNA |
| Synonyms: | AKR1C-pseudo|BABP|DD|DD-2|DD/BABP|DD2|DDH2|HAKRD|HBAB|MCDR2|SRXY8|TDD |
| Chromosome: | chr10 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 4987400 | End Site(bp): | 5018031 |
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| Gene Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
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