Entry Detail



General Information

Database ID:BRCA47586
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:RPS6KA4
Full Name:ribosomal protein S6 kinase A4
Category:mRNA
Synonyms:MSK2|RSK-B|S6K-alpha-4
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):64359148End Site(bp):64372215
Gene Summary:This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
External Links:
Ensembl ID:ENSG00000162302
HGNC ID:HGNC:10433
Entrez Gene:8986



Expression Profile of RPS6KA4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
NO
YES
hsa-miR-106b-5p
YES
NO
YES
hsa-miR-124-3p
YES
YES
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-17-5p
YES
NO
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-208a-3p
YES
YES
NO
hsa-miR-208b-3p
YES
YES
NO
hsa-miR-20a-5p
YES
NO
YES
hsa-miR-20b-5p
YES
NO
YES
hsa-miR-25-3p
YES
YES
YES
hsa-miR-32-5p
YES
YES
YES
hsa-miR-34a-5p
YES
YES
YES
hsa-miR-34c-5p
YES
YES
YES
hsa-miR-363-3p
YES
YES
YES
hsa-miR-367-3p
YES
YES
YES
hsa-miR-429
YES
YES
NO
hsa-miR-449a
YES
YES
YES
hsa-miR-449b-5p
YES
YES
YES
hsa-miR-455-3p
YES
NO
YES
hsa-miR-491-5p
YES
NO
NO
hsa-miR-499a-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-519d-3p
YES
NO
YES
hsa-miR-520f-3p
YES
NO
YES
hsa-miR-542-3p
YES
YES
YES
hsa-miR-92a-3p
YES
YES
YES
hsa-miR-92b-3p
YES
YES
YES
hsa-miR-93-5p
YES
NO
YES
hsa-miR-9-5p
YES
YES
YES
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