ctcRbase

Entry Detail

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General Information

Database ID: BRCA48117 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: TKTL1 Full Name: transketolase like 1 Category: mRNA Synonyms: TKR|TKT2 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 154295671 End Site(bp): 154330350 Gene Summary: The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000007350 HGNC ID: HGNC:11835 Entrez Gene: 8277

Expression Profile of TKTL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO Display: