ctcRbase

Entry Detail

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General Information

Database ID: BRCA48438 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: BMF Full Name: Bcl2 modifying factor Category: mRNA Synonyms: - Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 40087890 End Site(bp): 40108892 Gene Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000104081 HGNC ID: HGNC:24132 Entrez Gene: 90427

Expression Profile of BMF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-185-5p YES NO YES hsa-miR-193a-5p YES NO YES hsa-miR-205-5p YES NO YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-329-3p YES YES YES hsa-miR-346 YES YES NO hsa-miR-362-3p YES YES YES hsa-miR-370-3p YES NO YES hsa-miR-421 YES YES YES hsa-miR-495-3p YES NO NO hsa-miR-625-5p YES NO NO hsa-miR-7-5p YES YES NO hsa-miR-874-3p YES NO YES Display: