Entry Detail



General Information

Database ID:BRCA48827
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:CDT1
Full Name:chromatin licensing and DNA replication factor 1
Category:mRNA
Synonyms:DUP|RIS2
Chromosome:chr16
Strand:+
Coordinate:
Start Site(bp):88803213End Site(bp):88809258
Gene Summary:The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]
External Links:
Ensembl ID:ENSG00000167513
HGNC ID:HGNC:24576
Entrez Gene:81620



Expression Profile of CDT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-224-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
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