| ncRNA Symbol: | APLP1 |
| Full Name: | amyloid beta precursor like protein 1 |
| Category: | mRNA |
| Synonyms: | APLP |
| Chromosome: | chr19 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 35867899 | End Site(bp): | 35879791 |
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| Gene Summary: | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
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