| ncRNA Symbol: | APBA2 |
| Full Name: | amyloid beta precursor protein binding family A member 2 |
| Category: | mRNA |
| Synonyms: | D15S1518E|HsT16821|LIN-10|MGC:14091|MINT2|X11-BETA|X11L |
| Chromosome: | chr15 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 28884483 | End Site(bp): | 29118315 |
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| Gene Summary: | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017] |
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