Entry Detail



General Information

Database ID:LUSC07738
Cancer Type:non-small cell lung cancer
Dataset:GSE74639
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:BPIFA1
Full Name:BPI fold containing family A member 1
Category:mRNA
Synonyms:LUNX|NASG|PLUNC|SPLUNC1|SPURT|bA49G10.5
Chromosome:chr20
Strand:+
Coordinate:
Start Site(bp):33235995End Site(bp):33243311
Gene Summary:This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]
External Links:
Ensembl ID:ENSG00000198183
HGNC ID:HGNC:15749
Entrez Gene:51297



Expression Profile of BPIFA1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A