ctcRbase

Entry Detail

---



General Information

Database ID: PAAD00089 Cancer Type: pancreatic cancer Dataset: GSE40174 CTCs/CTM Isolation Method: TCGA-Chip

Gene Information

ncRNA Symbol: PTPRJ Full Name: protein tyrosine phosphatase, receptor type J Category: mRNA Synonyms: CD148|DEP1|HPTPeta|R-PTP-ETA|SCC1 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 47980558 End Site(bp): 48170841 Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000149177 HGNC ID: HGNC:9673 Entrez Gene: 5795

Expression Profile of PTPRJ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-139-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-25-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-328-3p YES YES NO hsa-miR-329-3p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-365a-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-370-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-454-3p YES YES YES hsa-miR-455-5p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-532-5p YES NO YES hsa-miR-582-5p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-93-5p YES YES YES hsa-miR-9-5p YES NO YES Display: