ctcRbase

Entry Detail

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General Information

Database ID: PAAD00128 Cancer Type: pancreatic cancer Dataset: GSE40174 CTCs/CTM Isolation Method: TCGA-Chip

Gene Information

ncRNA Symbol: ITIH1 Full Name: inter-alpha-trypsin inhibitor heavy chain 1 Category: mRNA Synonyms: H1P|IATIH|IGHEP1|ITI-HC1|ITIH|SHAP Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 52777592 End Site(bp): 52792068 Gene Summary: This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015] External Links: Ensembl ID: ENSG00000055957 HGNC ID: HGNC:6166 Entrez Gene: 3697

Expression Profile of ITIH1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO Display: