Entry Detail



General Information

Database ID:PAAD02802
Cancer Type:pancreatic cancer
Dataset:GSE60407
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:ADH1B
Full Name:alcohol dehydrogenase 1B (class I), beta polypeptide
Category:mRNA
Synonyms:ADH2|HEL-S-117
Chromosome:chr4
Strand:-
Coordinate:
Start Site(bp):99304964End Site(bp):99352760
Gene Summary:The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
External Links:
Ensembl ID:ENSG00000196616
HGNC ID:HGNC:250
Entrez Gene:125



Expression Profile of ADH1B Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-32-5p
YES
YES
NO
hsa-miR-363-3p
YES
YES
NO
hsa-miR-367-3p
YES
YES
NO
hsa-miR-429
YES
YES
NO
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