| ncRNA Symbol: | CLCN4 |
| Full Name: | chloride voltage-gated channel 4 |
| Category: | mRNA |
| Synonyms: | CLC4|ClC-4|ClC-4A|MRX15|MRX49|MRXSRC |
| Chromosome: | chrX |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 10156945 | End Site(bp): | 10237660 |
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| Gene Summary: | The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012] |
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