| ncRNA Symbol: | ST6GALNAC4 | | Full Name: | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | | Category: | mRNA | | Synonyms: | IV|SIAT3-C|SIAT3C|SIAT7-D|SIAT7D|ST6GALNACIV|ST6GalNAc | | Chromosome: | chr9 | | Strand: | - | | Coordinate: | | Start Site(bp): | 127907886 | End Site(bp): | 127917038 |
| | Gene Summary: | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | | External Links: | |
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