ctcRbase

Entry Detail

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General Information

Database ID: PRAD02738 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PDE5A Full Name: phosphodiesterase 5A Category: mRNA Synonyms: CGB-PDE|CN5A|PDE5 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 119494395 End Site(bp): 119628991 Gene Summary: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000138735 HGNC ID: HGNC:8784 Entrez Gene: 8654

Expression Profile of PDE5A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-1-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-217 YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-454-3p YES NO YES hsa-miR-543 YES YES NO Display: