| ncRNA Symbol: | FLI1 | | Full Name: | Fli-1 proto-oncogene, ETS transcription factor | | Category: | mRNA | | Synonyms: | BDPLT21|EWSR2|SIC-1 | | Chromosome: | chr11 | | Strand: | + | | Coordinate: | | Start Site(bp): | 128686535 | End Site(bp): | 128813267 | | | Gene Summary: | This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] | | External Links: | |
|