ctcRbase

Entry Detail

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General Information

Database ID: PRAD03273 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: DPYD Full Name: dihydropyrimidine dehydrogenase Category: mRNA Synonyms: DHP|DHPDHASE|DPD Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 97077743 End Site(bp): 97921049 Gene Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] External Links: Ensembl ID: ENSG00000188641 HGNC ID: HGNC:3012 Entrez Gene: 1806

Expression Profile of DPYD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-96-5p YES YES NO Display: