ctcRbase

Entry Detail

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General Information

Database ID: PRAD03690 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ALDH1A2 Full Name: aldehyde dehydrogenase 1 family member A2 Category: mRNA Synonyms: RALDH(II)|RALDH2|RALDH2-T Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 57953424 End Site(bp): 58497866 Gene Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000128918 HGNC ID: HGNC:15472 Entrez Gene: 8854

Expression Profile of ALDH1A2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-137 YES YES YES hsa-miR-18b-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-542-3p YES YES NO Display: