| ncRNA Symbol: | IL1RN |
| Full Name: | interleukin 1 receptor antagonist |
| Category: | mRNA |
| Synonyms: | DIRA|ICIL-1RA|IL-1RN|IL-1ra|IL-1ra3|IL1F3|IL1RA|IRAP|MVCD4 |
| Chromosome: | chr2 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 113107214 | End Site(bp): | 113134016 |
|
| Gene Summary: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016] |
| External Links: | |