ctcRbase

Entry Detail

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General Information

Database ID: PRAD04200 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MAP4K2 Full Name: mitogen-activated protein kinase kinase kinase kinase 2 Category: mRNA Synonyms: BL44|GCK|RAB8IP Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 64784914 End Site(bp): 64803241 Gene Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] External Links: Ensembl ID: ENSG00000168067 HGNC ID: HGNC:6864 Entrez Gene: 5871

Expression Profile of MAP4K2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-25-3p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES Display: