| ncRNA Symbol: | CRKL | | Full Name: | CRK like proto-oncogene, adaptor protein | | Category: | mRNA | | Synonyms: | - | | Chromosome: | chr22 | | Strand: | + | | Coordinate: | | Start Site(bp): | 20917426 | End Site(bp): | 20953749 | | | Gene Summary: | This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009] | | External Links: | |
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