ctcRbase

Entry Detail

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General Information

Database ID: PRAD05167 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: IL10RA Full Name: interleukin 10 receptor subunit alpha Category: mRNA Synonyms: CD210|CD210a|CDW210A|HIL-10R|IL-10R1|IL10R Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 117986348 End Site(bp): 118003037 Gene Summary: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009] External Links: Ensembl ID: ENSG00000110324 HGNC ID: HGNC:5964 Entrez Gene: 3587

Expression Profile of IL10RA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES Display: