ctcRbase

Entry Detail

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General Information

Database ID: PRAD05211 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: FADS2 Full Name: fatty acid desaturase 2 Category: mRNA Synonyms: D6D|DES6|FADSD6|LLCDL2|SLL0262|TU13 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 61792980 End Site(bp): 61867354 Gene Summary: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] External Links: Ensembl ID: ENSG00000134824 HGNC ID: HGNC:3575 Entrez Gene: 9415

Expression Profile of FADS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-219a-5p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES YES Display: