ctcRbase

Entry Detail

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General Information

Database ID: PRAD05680 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: DEPDC5 Full Name: DEP domain containing 5 Category: mRNA Synonyms: DEP.5|FFEVF|FFEVF1 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 31753951 End Site(bp): 31907034 Gene Summary: This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] External Links: Ensembl ID: ENSG00000100150 HGNC ID: HGNC:18423 Entrez Gene: 9681

Expression Profile of DEPDC5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-122-5p YES YES NO hsa-miR-15a-5p YES NO NO hsa-miR-15b-5p YES NO NO hsa-miR-16-5p YES NO NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-195-5p YES NO NO hsa-miR-214-3p YES NO NO hsa-miR-31-5p YES YES NO hsa-miR-424-5p YES NO NO hsa-miR-497-5p YES NO NO hsa-miR-503-5p YES NO NO Display: