| ncRNA Symbol: | FGD2 | | Full Name: | FYVE, RhoGEF and PH domain containing 2 | | Category: | mRNA | | Synonyms: | ZFYVE4 | | Chromosome: | chr6 | | Strand: | + | | Coordinate: | | Start Site(bp): | 37005646 | End Site(bp): | 37029070 | | | Gene Summary: | The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016] | | External Links: | |
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