ctcRbase

Entry Detail

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General Information

Database ID: PRAD05903 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TMEM173 Full Name: transmembrane protein 173 Category: mRNA Synonyms: ERIS|MITA|MPYS|NET23|SAVI|STING|STING-beta|hMITA|hSTING Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 139475534 End Site(bp): 139482935 Gene Summary: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] External Links: Ensembl ID: ENSG00000184584 HGNC ID: HGNC:27962 Entrez Gene: 340061

Expression Profile of TMEM173 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO Display: