ctcRbase

Entry Detail

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General Information

Database ID: PRAD05960 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TECPR2 Full Name: tectonin beta-propeller repeat containing 2 Category: mRNA Synonyms: KIAA0329|SPG49 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 102362963 End Site(bp): 102502481 Gene Summary: The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] External Links: Ensembl ID: ENSG00000196663 HGNC ID: HGNC:19957 Entrez Gene: 9895

Expression Profile of TECPR2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-124-3p YES NO YES hsa-miR-1294 YES NO NO hsa-miR-137 YES NO YES hsa-miR-24-3p YES NO YES hsa-miR-25-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-369-3p YES NO YES hsa-miR-411-5p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-98-5p YES NO YES Display: