ctcRbase

Entry Detail

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General Information

Database ID: PRAD06206 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: NFASC Full Name: neurofascin Category: mRNA Synonyms: NF|NRCAML Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 204828651 End Site(bp): 205022822 Gene Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009] External Links: Ensembl ID: ENSG00000163531 HGNC ID: HGNC:29866 Entrez Gene: 23114

Expression Profile of NFASC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-190a-5p YES NO YES hsa-miR-190b YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-497-5p YES NO YES Display: