ctcRbase

Entry Detail

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General Information

Database ID: PRAD06435 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SERPINE1 Full Name: serpin family E member 1 Category: mRNA Synonyms: PAI|PAI-1|PAI1|PLANH1 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 101127089 End Site(bp): 101139266 Gene Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000106366 HGNC ID: HGNC:8583 Entrez Gene: 5054

Expression Profile of SERPINE1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-148a-3p NO YES YES hsa-miR-148b-3p NO YES YES hsa-miR-150-5p YES YES NO hsa-miR-152-3p NO YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-342-3p YES YES YES hsa-miR-34a-5p YES NO YES hsa-miR-34c-5p YES NO YES hsa-miR-425-5p YES YES YES hsa-miR-449a YES NO YES hsa-miR-449b-5p YES NO YES hsa-miR-488-3p YES YES NO Display: