ctcRbase

Entry Detail

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General Information

Database ID: PRAD06438 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TNFRSF1B Full Name: TNF receptor superfamily member 1B Category: mRNA Synonyms: CD120b|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80|p75|p75TNFR Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 12167003 End Site(bp): 12209228 Gene Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000028137 HGNC ID: HGNC:11917 Entrez Gene: 7133

Expression Profile of TNFRSF1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-122-5p YES YES NO hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-454-3p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-98-5p YES YES YES Display: