ctcRbase

Entry Detail

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General Information

Database ID: PRAD06455 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: FOXP2 Full Name: forkhead box P2 Category: mRNA Synonyms: CAGH44|SPCH1|TNRC10 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 114086327 End Site(bp): 114693772 Gene Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000128573 HGNC ID: HGNC:13875 Entrez Gene: 93986

Expression Profile of FOXP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-101-3p YES YES NO hsa-miR-122-5p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-132-3p YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES NO YES hsa-miR-212-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-379-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-493-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-590-5p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES YES YES hsa-miR-96-5p YES YES YES hsa-miR-98-5p YES YES NO Display: