ctcRbase

Entry Detail

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General Information

Database ID: PRAD06469 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: RHOH Full Name: ras homolog family member H Category: mRNA Synonyms: ARHH|TTF Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 40191053 End Site(bp): 40246967 Gene Summary: The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]400 External Links: Ensembl ID: ENSG00000168421 HGNC ID: HGNC:686 Entrez Gene: 399

Expression Profile of RHOH Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO Display: