ctcRbase

Entry Detail

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General Information

Database ID: PRAD06676 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: FBXL2 Full Name: F-box and leucine rich repeat protein 2 Category: mRNA Synonyms: FBL2|FBL3 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 33277025 End Site(bp): 33403662 Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] External Links: Ensembl ID: ENSG00000153558 HGNC ID: HGNC:13598 Entrez Gene: 25827

Expression Profile of FBXL2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-141-3p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-218-5p YES NO YES hsa-miR-219a-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-590-5p YES YES NO Display: