ctcRbase

Entry Detail

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General Information

Database ID: PRAD06906 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: STK11 Full Name: serine/threonine kinase 11 Category: mRNA Synonyms: LKB1|PJS|hLKB1 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 1177558 End Site(bp): 1228435 Gene Summary: This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000118046 HGNC ID: HGNC:11389 Entrez Gene: 6794

Expression Profile of STK11 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-137 YES NO YES hsa-miR-142-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES Display: