ctcRbase

Entry Detail

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General Information

Database ID: PRAD07127 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PNPLA6 Full Name: patatin like phospholipase domain containing 6 Category: mRNA Synonyms: BNHS|LNMS|NTE|NTEMND|OMCS|SPG39|iPLA2delta|sws Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 7534004 End Site(bp): 7561764 Gene Summary: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000032444 HGNC ID: HGNC:16268 Entrez Gene: 10908

Expression Profile of PNPLA6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-200a-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-454-3p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-497-5p YES YES YES Display: