ctcRbase

Entry Detail

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General Information

Database ID: PRAD07202 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PRKCE Full Name: protein kinase C epsilon Category: mRNA Synonyms: PKCE|nPKC-epsilon Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 45651345 End Site(bp): 46187990 Gene Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000171132 HGNC ID: HGNC:9401 Entrez Gene: 5581

Expression Profile of PRKCE Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-1271-5p YES YES YES hsa-miR-129-2-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-21-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES NO YES hsa-miR-218-5p YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-25-3p YES YES YES hsa-miR-31-5p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-875-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-96-5p YES YES YES Display: