ctcRbase

Entry Detail

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General Information

Database ID: PRAD07221 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: DDX3Y Full Name: DEAD-box helicase 3 Y-linked Category: mRNA Synonyms: DBY Chromosome: chrY Strand: + Coordinate: Start Site(bp): 12904108 End Site(bp): 12920478 Gene Summary: The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] External Links: Ensembl ID: ENSG00000067048 HGNC ID: HGNC:2699 Entrez Gene: 8653

Expression Profile of DDX3Y Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7g-5p YES YES NO hsa-miR-103a-3p YES YES YES hsa-miR-106b-5p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES NO YES hsa-miR-1297 YES NO YES hsa-miR-133a-3p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES NO YES hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18b-5p YES YES YES hsa-miR-199a-3p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-23b-3p YES YES YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-29b-3p YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-325 YES YES YES hsa-miR-331-3p YES YES NO hsa-miR-337-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-365a-3p YES YES YES hsa-miR-374a-3p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-500a-3p YES NO YES hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-512-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-556-5p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-934 YES NO YES hsa-miR-93-5p YES YES YES Display: