ctcRbase

Entry Detail

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General Information

Database ID: PRAD07349 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MXD4 Full Name: MAX dimerization protein 4 Category: mRNA Synonyms: MAD4|MST149|MSTP149|bHLHc12 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 2247432 End Site(bp): 2262294 Gene Summary: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000123933 HGNC ID: HGNC:13906 Entrez Gene: 10608

Expression Profile of MXD4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-124-3p YES YES YES hsa-miR-1249-3p YES NO YES hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-138-5p YES NO YES hsa-miR-1-3p YES NO YES hsa-miR-183-5p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-206 YES YES YES hsa-miR-429 YES NO YES hsa-miR-483-3p YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-532-3p YES NO YES hsa-miR-613 YES NO YES hsa-miR-655-3p YES NO YES Display: