Entry Detail



General Information

Database ID:PRAD07434
Cancer Type:prostate cancer
Dataset:GSE104209
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:CRISP3
Full Name:cysteine rich secretory protein 3
Category:mRNA
Synonyms:Aeg2|CRISP-3|CRS3|SGP28|dJ442L6.3
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):49727384End Site(bp):49744437
Gene Summary:This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
External Links:
Ensembl ID:ENSG00000096006
HGNC ID:HGNC:16904
Entrez Gene:10321



Expression Profile of CRISP3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-10a-5p
YES
YES
NO
hsa-miR-10b-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-375
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
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