| ncRNA Symbol: | BIRC3 |
| Full Name: | baculoviral IAP repeat containing 3 |
| Category: | mRNA |
| Synonyms: | AIP1|API2|CIAP2|HAIP1|HIAP1|IAP-1|MALT2|MIHC|RNF49|c-IAP2 |
| Chromosome: | chr11 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 102317450 | End Site(bp): | 102339403 |
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| Gene Summary: | This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011] |
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