| ncRNA Symbol: | JAK3 |
| Full Name: | Janus kinase 3 |
| Category: | mRNA |
| Synonyms: | JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK |
| Chromosome: | chr19 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 17824780 | End Site(bp): | 17848071 |
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| Gene Summary: | The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008] |
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