ctcRbase

Entry Detail

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General Information

Database ID: PRAD08219 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ARHGEF11 Full Name: Rho guanine nucleotide exchange factor 11 Category: mRNA Synonyms: GTRAP48|PDZ-RHOGEF Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 156934840 End Site(bp): 157045370 Gene Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000132694 HGNC ID: HGNC:14580 Entrez Gene: 9826

Expression Profile of ARHGEF11 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-1321 YES NO NO hsa-miR-132-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-212-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-381-3p YES YES NO hsa-miR-423-5p YES NO NO hsa-miR-488-3p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-93-5p YES YES YES Display: