ctcRbase

Entry Detail

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General Information

Database ID: PRAD08367 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ARNTL Full Name: aryl hydrocarbon receptor nuclear translocator like Category: mRNA Synonyms: BMAL1|BMAL1c|JAP3|MOP3|PASD3|TIC|bHLHe5 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 13276652 End Site(bp): 13387266 Gene Summary: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000133794 HGNC ID: HGNC:701 Entrez Gene: 406

Expression Profile of ARNTL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-448 YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-760 YES NO YES Display: